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Current and Emerging Applications

Given the pace of research in this field, experts predict a broad array of applications in 'regenerative medicine' to be enabled by stem cells in the near future.

Adult stem cells from bone marrow and umbilical cord blood have been used for decades to treat patients for dozens of diseases, most notably leukemia and other blood-related conditions.
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Adult stem cells from teeth have been used to successfully grow jawbone and treat periodontal disease in people. Scientists and clinicians are investigating many additional uses for dental stem cells, for example treating root canals and even regenerating whole new teeth.

Dental stem cells are also being studied as a way to help treat a number of medical diseases and conditions:

• Diabetes
• Spinal cord injury
• Muscular dystrophy
• Stroke
• Myocardial infarction (heart attack)
• Liver disease
• Cornea repair
• Parkinson's disease
• Alzheimer's

The earliest applications for dental stem cells are expected to be the repair of damaged tooth structures and craniofacial defects, bone regeneration, and possibly the treatment of neural tissue injury or degenerative diseases.

"By age 65, the prevalence of periodontal disease has doubled; more than one out of every 6 seniors has gum disease. In fact, over one fourth of adults over age 65 have lost all their teeth."

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"...Periodontal (gum) diseases are associated with diabetes, and there is emerging evidence of a relationship between severe periodontal disease and cardiovascular disease and stroke."

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"Stem cell research may eventually lead to therapies that could be used to treat diseases that afflict approximately 128 million Americans."

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